Highlighted Articles
Vachez YM*, Tooley JR*, Abiraman K, Matikainen-Ankeny B, Casey E, Earnest T, Ramos LM, Silberberg H, Godynyuk E, Uddin O, Marconi L, Le Pichon C, Creed M.
Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption.
Nature Neuroscience. 2021. 24:379-390.
vacheztooley_natneuro_2020.pdf
Tooley J, Marconi L, Alipio JB, Matikainen-Ankney B, Georgiou P, Kravitz AV, Creed M.
Glutamatergic ventral pallidal neurons modulate activity of the habenula - tegmental circuitry and constrain reward seeking.
Biological Psychiatry. 2018. 15(12):1012-1023
tooley_biolpsych_2018.pdf
Creed MC.
Current and emerging neuromodulation therapies for addiction: insight from pre-clinical studies.
Current Opinion in Neurobiology. 2018. In Press.
creed_curropinneurobiol_2018.pdf
Lee D*, Creed M*, Jung K*, Wendler DJ, Oh WC, Mignocchi NL, Lüscher C, and Kwon HB.
Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain.
Nature Methods. 2017. 14(5):495-503. *Co-first author
lee_et_al-2017-nature_methods.pdf
Creed M, Pascoli VP, Lüscher C.
Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology.
Science. 2015. 347(6222):659-64.
creed_science_2015.pdf
Creed M, Ntamati R, Chandra R, Lobo MK, Lüshcer C.
Convergence of rewarding and anhedonic effects of cocaine in the ventral pallidum.
Neuron. 2016. 92(1): 214-226.
creed_neuron_2016.pdf
Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption.
Nature Neuroscience. 2021. 24:379-390.
vacheztooley_natneuro_2020.pdf
Tooley J, Marconi L, Alipio JB, Matikainen-Ankney B, Georgiou P, Kravitz AV, Creed M.
Glutamatergic ventral pallidal neurons modulate activity of the habenula - tegmental circuitry and constrain reward seeking.
Biological Psychiatry. 2018. 15(12):1012-1023
tooley_biolpsych_2018.pdf
Creed MC.
Current and emerging neuromodulation therapies for addiction: insight from pre-clinical studies.
Current Opinion in Neurobiology. 2018. In Press.
creed_curropinneurobiol_2018.pdf
Lee D*, Creed M*, Jung K*, Wendler DJ, Oh WC, Mignocchi NL, Lüscher C, and Kwon HB.
Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain.
Nature Methods. 2017. 14(5):495-503. *Co-first author
lee_et_al-2017-nature_methods.pdf
Creed M, Pascoli VP, Lüscher C.
Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology.
Science. 2015. 347(6222):659-64.
creed_science_2015.pdf
Creed M, Ntamati R, Chandra R, Lobo MK, Lüshcer C.
Convergence of rewarding and anhedonic effects of cocaine in the ventral pallidum.
Neuron. 2016. 92(1): 214-226.
creed_neuron_2016.pdf
Research Articles
Matikainen-Ankney BA, Earnest T, Ali M, Casey E, Wang J et al.
An open-source device for measuring food intake and operant behavior in rodent home-cages.
eLife. 2021. In Press.
Matikainen-Ankney_2021
Vachez YM*, Tooley JR*, Abiraman K, Matikainen-Ankeny B, Casey E, Earnest T, Ramos LM, Silberberg H, Godynyuk E, Uddin O, Marconi L, Le Pichon C, Creed M.
Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption.
Nature Neuroscience. 2021. 24:379-390.
vacheztooley_natneuro_2020.pdf
Bariselli S, Miyazaki NL, Creed MC, Kravitz AV.
Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity.
Nat Commun. 2020 Aug 10;11(1):3996
bariselli_natcomm_2021.pdf
Fobbs WC, Bariselli S, Licholai JA, Miyazaki NL, Matikainen-Ankney BA, Creed MC, Kravitz AV.
Continuous representations of speed by striatal medium spiny neurons.
J Neurosci. 2020 Feb 19;40(8):1679-1688.
https://www.jneurosci.org/content/40/8/1679.long
Ramirez-Zamora A, et al.
Proceedings of the Sixth Deep Brain Stimulation Think Tank: Modulation of brain networks and applications of advanced neuroimaging, neurophysiology and optogenetics.
Front Neurosci. 2019. 13:936.
https://www.frontiersin.org/articles/10.3389/fnins.2019.00936/full
Godynyuk E, Bluitt MN, Tooley JR, Kravitz AV, Creed MC.
An open-source, automated, home-cage sipper device for monitoring liquid ingestive behavior in rodents.
eNeuro. 2019. 10;6(5).
https://www.eneuro.org/content/6/5/ENEURO.0292-19.2019.long
LeGates TA, Kvarta MD, Tooley JR, Francis TC, Lobo MK, Creed MC, Thompson SM.
Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses.
Nature. 2018. In Press.
www.nature.com/articles/s41586-018-0740-8
Wulff AB, Tooley J, Marconi LJ, Creed MC.
Ventral pallidal modulation of aversion processing.
Brain Research. 2018. In Press.
wulff_brainres_2018.pdf
Tooley J, Marconi L, Alipio JB, Matikainen-Ankney B, Georgiou P, Kravitz AV, Creed MC.
Glutamatergic ventral pallidal neurons modulate activity of the habenula - tegmental circuitry and constrain reward seeking.
Biological Psychiatry. 2018. 83(12):1012-1023.
tooley_biolpsych_2018.pdf
Ntamati NR, Creed M, Achargui R, Lüscher C.
Periaqueductal efferents to dopamine and GABA neurons of the VTA.
Plos ONE. 2018. 13(1): e0190297.
ntamati_2018.pdf
Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, Golden SA, Iñiguez SD, Russo SJ, Turecki G, Mathur BN, Creed M, Dietz DM, Lobo MK.
Drp1 mitochondrial fission in D1 neurons mediates behavioral and cellular plasticity during early cocaine abstinence.
Neuron. 2017. 96(6):1327-1341.
chandra_neuron_2017.pdf
Hamman M, Plank J, Richter F, Bode C, Smilganic S, Creed M, Nobrega JN and Richter A.
Alterations of M1 and M4 acetylcholine receptors in the genetically dystonic (dtsz) hamster and moderate antidystonic efficacy of M1 and M4 anticholinergics.
Neuroscience. 2017. 357:84-98.
Lee D*, Creed M*, Jung K*, Wendler DJ, Oh WC, Mignocchi NL, Lüscher C, and Kwon HB.
Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain.
Nature Methods. 2017. 14(5):495-503.
*Co-first author
lee_et_al-2017-nature_methods.pdf
Creed M, Ntamati R, Chandra R, Lobo MK, Lüshcer C.
Convergence of rewarding and anhedonic effects of cocaine in the ventral pallidum.
Neuron. 2016. 92(1): 214-226.
creed_neuron_2016.pdf
Creed M*, Kaufling J*, Fois G, Jalabert M, Yuan T, Lüscher C, Georges F, and Bellone C.
Cocaine exposure enhances the activity of VTA dopamine neurons via calcium impermeable NMDARs.
Journal of Neuroscience. 2016. 36(42):10759-10768.
*Co-first author
creed_jns_2016.pdf
Visanji NP, Sarvestani IK, Creed MC, Shoaei ZS, Nobrega JN, Hamani C, Hazrati LN.
Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson’s disease.
Frontiers in Cellular Neuroscience. 2015. 9:21.
visanji_frontiers_2015.pdf
Creed M, Pascoli VP, Lüscher C.
Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology.
Science. 2015. 347(6222):659-64.
creed_science_2015.pdf
Nona C, Creed MC, Hamani C, Nobrega JN.
Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice.
Behavioural Pharmacology, 2015. 26(1-2):184-92.
nona_behavioralpharm_2014.pdf
Wheeler AL, Creed MC, Voineskos AN, Nobrega JN.
Changes in brain functional connectivity after chronic haloperidol in rats: a network analysis.
International Journal of Neuropsychopharmacology, 2014. 17(8):1129-38.
wheeler_intjourneuropsychopharm_2014.pdf
Aleksandrova LR, Creed MC, Fletcher PJ, Lobo DS, Hamani C, Nobrega JN.
Deep brain stimulation of the subthalamic nucleus increases premature responding in a rat gambling task.
Behavioral Brain Research. 2013. 245:76-82.
aleksandrova_behavbrainres_2013.pdf
Lambrecht C, Creed M, Sander SE, Nobrega JN, Richter A.
Pathophysiological distribution and relevance of K (v) 7.2/3/5 potassium channels in the CNS of 6-OHDA lesioned rats.
Nauyn-Schmiedebergs Archives of Pharmacology. 2012. 385:50-55.
Creed MC, Hamani C, Nobrega JN.
Effects of repeated deep brain stimulation on depressive- and anxiety-like behavior in rats: comparing entopeduncular and subthalamic nuclei.
Brain Stimulation. 2012. 6(4):506-14.
creed_brainstim_2013.pdf
Creed MC, Hamani C, Bridgeman A, Fletcher PJ, Nobrega JN.
Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: comparison of the subthalamic and entopeduncular nuclei.
Journal of Neuroscience. 2012. 32(28)9874-81.
creed_jns_2012.pdf
Creed MC, Hamani C, Nobrega JN.
Early gene mapping after deep brain stimulation in a rat model of tardive dyskinesia: comparison with transient local inactivation. European Journal of Neuropsychopharmacology. 2011. 22(7):506-517.
creed_eurneuropsychopharm_2012.pdf
Creed-Carson M, Orha A, Nobrega JN.
Effects of 5-HT(2A) and 5-HT(2C) receptor antagonists on acute and chronic dyskinetic effects induced by haloperidol in rats.
Behavioral Brain Research. 2011. 219(2):273-279.
creed_behavbrainres_2011.pdf
Kessas M, Creed M, Nobrega JN.
An examination of synaptic proteins following chronic haloperidol in a rat model of tardive dyskinesia.
Psychology & Neuroscience. 2010. 3(2):229-237.
kessas_psychneuro_2010.pdf
Creed M, Hamani C, Nobrega JN.
Acute deep-brain stimulation alleviates orofacial dyskinesias induced by chronic haloperidol in the rat.
European Journal of Neuropsychopharmacology. 2010. 21(5):393-400.
creed_eurneuropsychopharm_2011.pdf
An open-source device for measuring food intake and operant behavior in rodent home-cages.
eLife. 2021. In Press.
Matikainen-Ankney_2021
Vachez YM*, Tooley JR*, Abiraman K, Matikainen-Ankeny B, Casey E, Earnest T, Ramos LM, Silberberg H, Godynyuk E, Uddin O, Marconi L, Le Pichon C, Creed M.
Ventral arkypallidal neurons inhibit accumbal firing to promote reward consumption.
Nature Neuroscience. 2021. 24:379-390.
vacheztooley_natneuro_2020.pdf
Bariselli S, Miyazaki NL, Creed MC, Kravitz AV.
Orbitofrontal-striatal potentiation underlies cocaine-induced hyperactivity.
Nat Commun. 2020 Aug 10;11(1):3996
bariselli_natcomm_2021.pdf
Fobbs WC, Bariselli S, Licholai JA, Miyazaki NL, Matikainen-Ankney BA, Creed MC, Kravitz AV.
Continuous representations of speed by striatal medium spiny neurons.
J Neurosci. 2020 Feb 19;40(8):1679-1688.
https://www.jneurosci.org/content/40/8/1679.long
Ramirez-Zamora A, et al.
Proceedings of the Sixth Deep Brain Stimulation Think Tank: Modulation of brain networks and applications of advanced neuroimaging, neurophysiology and optogenetics.
Front Neurosci. 2019. 13:936.
https://www.frontiersin.org/articles/10.3389/fnins.2019.00936/full
Godynyuk E, Bluitt MN, Tooley JR, Kravitz AV, Creed MC.
An open-source, automated, home-cage sipper device for monitoring liquid ingestive behavior in rodents.
eNeuro. 2019. 10;6(5).
https://www.eneuro.org/content/6/5/ENEURO.0292-19.2019.long
LeGates TA, Kvarta MD, Tooley JR, Francis TC, Lobo MK, Creed MC, Thompson SM.
Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses.
Nature. 2018. In Press.
www.nature.com/articles/s41586-018-0740-8
Wulff AB, Tooley J, Marconi LJ, Creed MC.
Ventral pallidal modulation of aversion processing.
Brain Research. 2018. In Press.
wulff_brainres_2018.pdf
Tooley J, Marconi L, Alipio JB, Matikainen-Ankney B, Georgiou P, Kravitz AV, Creed MC.
Glutamatergic ventral pallidal neurons modulate activity of the habenula - tegmental circuitry and constrain reward seeking.
Biological Psychiatry. 2018. 83(12):1012-1023.
tooley_biolpsych_2018.pdf
Ntamati NR, Creed M, Achargui R, Lüscher C.
Periaqueductal efferents to dopamine and GABA neurons of the VTA.
Plos ONE. 2018. 13(1): e0190297.
ntamati_2018.pdf
Chandra R, Engeln M, Schiefer C, Patton MH, Martin JA, Werner CT, Riggs LM, Francis TC, McGlincy M, Evans B, Nam H, Das S, Girven K, Konkalmatt P, Gancarz AM, Golden SA, Iñiguez SD, Russo SJ, Turecki G, Mathur BN, Creed M, Dietz DM, Lobo MK.
Drp1 mitochondrial fission in D1 neurons mediates behavioral and cellular plasticity during early cocaine abstinence.
Neuron. 2017. 96(6):1327-1341.
chandra_neuron_2017.pdf
Hamman M, Plank J, Richter F, Bode C, Smilganic S, Creed M, Nobrega JN and Richter A.
Alterations of M1 and M4 acetylcholine receptors in the genetically dystonic (dtsz) hamster and moderate antidystonic efficacy of M1 and M4 anticholinergics.
Neuroscience. 2017. 357:84-98.
Lee D*, Creed M*, Jung K*, Wendler DJ, Oh WC, Mignocchi NL, Lüscher C, and Kwon HB.
Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain.
Nature Methods. 2017. 14(5):495-503.
*Co-first author
lee_et_al-2017-nature_methods.pdf
Creed M, Ntamati R, Chandra R, Lobo MK, Lüshcer C.
Convergence of rewarding and anhedonic effects of cocaine in the ventral pallidum.
Neuron. 2016. 92(1): 214-226.
creed_neuron_2016.pdf
Creed M*, Kaufling J*, Fois G, Jalabert M, Yuan T, Lüscher C, Georges F, and Bellone C.
Cocaine exposure enhances the activity of VTA dopamine neurons via calcium impermeable NMDARs.
Journal of Neuroscience. 2016. 36(42):10759-10768.
*Co-first author
creed_jns_2016.pdf
Visanji NP, Sarvestani IK, Creed MC, Shoaei ZS, Nobrega JN, Hamani C, Hazrati LN.
Deep brain stimulation of the subthalamic nucleus preferentially alters the translational profile of striatopallidal neurons in an animal model of Parkinson’s disease.
Frontiers in Cellular Neuroscience. 2015. 9:21.
visanji_frontiers_2015.pdf
Creed M, Pascoli VP, Lüscher C.
Refining deep brain stimulation to emulate optogenetic treatment of synaptic pathology.
Science. 2015. 347(6222):659-64.
creed_science_2015.pdf
Nona C, Creed MC, Hamani C, Nobrega JN.
Effects of high-frequency stimulation of the nucleus accumbens on the development and expression of ethanol sensitization in mice.
Behavioural Pharmacology, 2015. 26(1-2):184-92.
nona_behavioralpharm_2014.pdf
Wheeler AL, Creed MC, Voineskos AN, Nobrega JN.
Changes in brain functional connectivity after chronic haloperidol in rats: a network analysis.
International Journal of Neuropsychopharmacology, 2014. 17(8):1129-38.
wheeler_intjourneuropsychopharm_2014.pdf
Aleksandrova LR, Creed MC, Fletcher PJ, Lobo DS, Hamani C, Nobrega JN.
Deep brain stimulation of the subthalamic nucleus increases premature responding in a rat gambling task.
Behavioral Brain Research. 2013. 245:76-82.
aleksandrova_behavbrainres_2013.pdf
Lambrecht C, Creed M, Sander SE, Nobrega JN, Richter A.
Pathophysiological distribution and relevance of K (v) 7.2/3/5 potassium channels in the CNS of 6-OHDA lesioned rats.
Nauyn-Schmiedebergs Archives of Pharmacology. 2012. 385:50-55.
Creed MC, Hamani C, Nobrega JN.
Effects of repeated deep brain stimulation on depressive- and anxiety-like behavior in rats: comparing entopeduncular and subthalamic nuclei.
Brain Stimulation. 2012. 6(4):506-14.
creed_brainstim_2013.pdf
Creed MC, Hamani C, Bridgeman A, Fletcher PJ, Nobrega JN.
Contribution of decreased serotonin release to the antidyskinetic effects of deep brain stimulation in a rodent model of tardive dyskinesia: comparison of the subthalamic and entopeduncular nuclei.
Journal of Neuroscience. 2012. 32(28)9874-81.
creed_jns_2012.pdf
Creed MC, Hamani C, Nobrega JN.
Early gene mapping after deep brain stimulation in a rat model of tardive dyskinesia: comparison with transient local inactivation. European Journal of Neuropsychopharmacology. 2011. 22(7):506-517.
creed_eurneuropsychopharm_2012.pdf
Creed-Carson M, Orha A, Nobrega JN.
Effects of 5-HT(2A) and 5-HT(2C) receptor antagonists on acute and chronic dyskinetic effects induced by haloperidol in rats.
Behavioral Brain Research. 2011. 219(2):273-279.
creed_behavbrainres_2011.pdf
Kessas M, Creed M, Nobrega JN.
An examination of synaptic proteins following chronic haloperidol in a rat model of tardive dyskinesia.
Psychology & Neuroscience. 2010. 3(2):229-237.
kessas_psychneuro_2010.pdf
Creed M, Hamani C, Nobrega JN.
Acute deep-brain stimulation alleviates orofacial dyskinesias induced by chronic haloperidol in the rat.
European Journal of Neuropsychopharmacology. 2010. 21(5):393-400.
creed_eurneuropsychopharm_2011.pdf
Review Articles
Vachez YM, Creed MC.
Deep Brain Stimulation of the Subthalamic Nucleus Modulates Reward-Related Behavior: A Systematic Review.
Front Hum Neurosci. 2020 Nov 20;14:578564.
vachez_2020.pdf
Bariselli S, Fobbs WC, Creed MC, Kravitz AV.
A competitive model for striatal action selection.
Brain Research. 2018. In Press.
bariselli_brainresearch_2018.pdf
Creed MC.
Current and emerging neuromodulation therapies for addiction: insight from pre-clinical studies.
Current Opinion in Neurobiology. 2018. In Press.
creed_curropinneurobiol_2018.pdf
Creed MC.
Towards a targeted treatment for addiction.
Science. 2017. 357(6350): 464-465.
creed_science_2017.pdf
Creed M, Bonci A, Leggio L.
Modulating morphine context-induced drug memory with deep brain stimulation: more research questions by lowering stimulation frequencies?
Biological Psychiatry. 2016. 80(9): 647-649.
creed_biolpsych_2016.pdf
Lüscher C, Pascoli V, Creed MC.
Optogenetic dissection of neural circuitry: From synaptic causalities to blue prints for novel treatments of behavioral diseases. Current Opinion in Neurobiology. 2015. 35:95-100.
luscher_curropinneurobiol_2015.pdf
Creed MC, Ntami NR, Tan KR.
VTA GABA neurons modulate specific learning behaviours through the control of dopamine and cholinergic systems.
Frontiers in Behavioral Neuroscience. 2014. 8:8.
creed_frontiers_2014.pdf
Creed MC, Lüscher C.
Drug-evoked synaptic plasticity: beyond metaplasticity.
Current opinion in Neurobiology. 2013. 23(4):553-8.
creed_curropinneurobiol_2013.pdf
Creed MC, Nobrega JN.
The role of serotonin in the antidyskinetic effects of deep brain stimulation: Focus on antipsychotic-induced motor symptoms. Reviews in the Neurosciences. 2012. 24(2):153-66.
Creed MC, Nobrega JN.
Neurobiological basis of dyskinetic effects induced by antipsychotics: the contribution of animal models.
Current Medicinal Chemistry. 2012. 20(3):389-96.
creed_nobrega_2013.pdf
Creed M, Milgram NW.
Amyloid-modifying therapies for Alzheimer’s disease: therapeutic progress and its implications.
Age: Journal of the American Aging Association. 2010. 32(3):365-84.
creed_age_2009.pdf
Deep Brain Stimulation of the Subthalamic Nucleus Modulates Reward-Related Behavior: A Systematic Review.
Front Hum Neurosci. 2020 Nov 20;14:578564.
vachez_2020.pdf
Bariselli S, Fobbs WC, Creed MC, Kravitz AV.
A competitive model for striatal action selection.
Brain Research. 2018. In Press.
bariselli_brainresearch_2018.pdf
Creed MC.
Current and emerging neuromodulation therapies for addiction: insight from pre-clinical studies.
Current Opinion in Neurobiology. 2018. In Press.
creed_curropinneurobiol_2018.pdf
Creed MC.
Towards a targeted treatment for addiction.
Science. 2017. 357(6350): 464-465.
creed_science_2017.pdf
Creed M, Bonci A, Leggio L.
Modulating morphine context-induced drug memory with deep brain stimulation: more research questions by lowering stimulation frequencies?
Biological Psychiatry. 2016. 80(9): 647-649.
creed_biolpsych_2016.pdf
Lüscher C, Pascoli V, Creed MC.
Optogenetic dissection of neural circuitry: From synaptic causalities to blue prints for novel treatments of behavioral diseases. Current Opinion in Neurobiology. 2015. 35:95-100.
luscher_curropinneurobiol_2015.pdf
Creed MC, Ntami NR, Tan KR.
VTA GABA neurons modulate specific learning behaviours through the control of dopamine and cholinergic systems.
Frontiers in Behavioral Neuroscience. 2014. 8:8.
creed_frontiers_2014.pdf
Creed MC, Lüscher C.
Drug-evoked synaptic plasticity: beyond metaplasticity.
Current opinion in Neurobiology. 2013. 23(4):553-8.
creed_curropinneurobiol_2013.pdf
Creed MC, Nobrega JN.
The role of serotonin in the antidyskinetic effects of deep brain stimulation: Focus on antipsychotic-induced motor symptoms. Reviews in the Neurosciences. 2012. 24(2):153-66.
Creed MC, Nobrega JN.
Neurobiological basis of dyskinetic effects induced by antipsychotics: the contribution of animal models.
Current Medicinal Chemistry. 2012. 20(3):389-96.
creed_nobrega_2013.pdf
Creed M, Milgram NW.
Amyloid-modifying therapies for Alzheimer’s disease: therapeutic progress and its implications.
Age: Journal of the American Aging Association. 2010. 32(3):365-84.
creed_age_2009.pdf
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